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Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs

The onset of the adaptive immune response to Mycobacterium tuberculosis is delayed compared with that of other infections or immunization, and allows the bacterial population in the lungs to expand markedly during the preimmune phase of infection. We used adoptive transfer of M. tuberculosis Ag85B-s...

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Autors principals: Wolf, Andrea J., Desvignes, Ludovic, Linas, Beth, Banaiee, Niaz, Tamura, Toshiki, Takatsu, Kiyoshi, Ernst, Joel D.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234384/
https://ncbi.nlm.nih.gov/pubmed/18158321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071367
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