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Protection against cerebral malaria by the low-molecular-weight thiol pantethine

We report that administration of the low-molecular-weight thiol pantethine prevented the cerebral syndrome in Plasmodium berghei ANKA-infected mice. The protection was associated with an impairment of the host response to the infection, with in particular a decrease of circulating microparticles and...

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Détails bibliographiques
Auteurs principaux: Penet, Marie-France, Abou-Hamdan, Mhamad, Coltel, Nicolas, Cornille, Emilie, Grau, Georges E., de Reggi, Max, Gharib, Bouchra
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234136/
https://ncbi.nlm.nih.gov/pubmed/18195363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706867105
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