Selective aluminum passivation for targeted immobilization of single DNA polymerase molecules in zero-mode waveguide nanostructures

Optical nanostructures have enabled the creation of subdiffraction detection volumes for single-molecule fluorescence microscopy. Their applicability is extended by the ability to place molecules in the confined observation volume without interfering with their biological function. Here, we demonstr...

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Main Authors: Korlach, Jonas, Marks, Patrick J., Cicero, Ronald L., Gray, Jeremy J., Murphy, Devon L., Roitman, Daniel B., Pham, Thang T., Otto, Geoff A., Foquet, Mathieu, Turner, Stephen W.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234111/
https://ncbi.nlm.nih.gov/pubmed/18216253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710982105
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