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Determinants of Anion Permeation in the Second Transmembrane Domain of the Mouse Bestrophin-2 Chloride Channel

Bestrophins have been proposed to constitute a new family of Cl channels that are activated by cytosolic Ca. We showed previously that mutation of serine-79 to cysteine in mouse bestrophin-2 (mBest2) altered the relative permeability and conductance to SCN. In this paper, we have overexpressed vario...

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Détails bibliographiques
Auteurs principaux: Qu, Zhiqiang, Hartzell, Criss
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233901/
https://ncbi.nlm.nih.gov/pubmed/15452198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409108
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