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Mouse Bestrophin-2 Is a Bona fide Cl(−) Channel: Identification of a Residue Important in Anion Binding and Conduction

Bestrophins have recently been proposed to comprise a new family of Cl(−) channels. Our goal was to test whether mouse bestrophin-2 (mBest2) is a bona fide Cl(−) channel. We expressed mBest2 in three different mammalian cell lines. mBest2 was trafficked to the plasma membrane as shown by biotinylati...

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Detalhes bibliográficos
Main Authors: Qu, Zhiqiang, Fischmeister, Rodolphe, Hartzell, Criss
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217464/
https://ncbi.nlm.nih.gov/pubmed/15051805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409031
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