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Angiotensin II (AT1) Receptors and NADPH Oxidase Regulate Cl(−) Current Elicited by β1 Integrin Stretch in Rabbit Ventricular Myocytes

Direct stretch of β1 integrin activates an outwardly rectifying, tamoxifen-sensitive Cl(−) current (Cl(−) SAC) via focal adhesion kinase (FAK) and/or Src. The characteristics of Cl(−) SAC resemble those of the volume-sensitive Cl(−) current, I(Cl,swell). Because myocyte stretch releases angiotensin...

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Detalles Bibliográficos
Main Authors: Browe, David M., Baumgarten, Clive M.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2004
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233887/
https://ncbi.nlm.nih.gov/pubmed/15337822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409040
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