Hidden Markov Model Analysis of Intermediate Gating Steps Associated with the Pore Gate of Shaker Potassium Channels

Cooperativity among the four subunits helps give rise to the remarkable voltage sensitivity of Shaker potassium channels, whose open probability changes tenfold for a 5-mV change in membrane potential. The cooperativity in these channels is thought to arise from a concerted structural transition as...

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Bibliographic Details
Main Authors: Zheng, Jie, Vankataramanan, Lalitha, Sigworth, Fred J.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2001
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233839/
https://ncbi.nlm.nih.gov/pubmed/11696611
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