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Role of the S3-S4 Linker in Shaker Potassium Channel Activation

Structural models of voltage-gated channels suggest that flexibility of the S3-S4 linker region may be important in allowing the S4 region to undergo large conformational changes in its putative voltage-sensing function. We report here the initial characterization of 18 mutations in the S3-S4 linker...

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Detalles Bibliográficos
Main Authors: Mathur, Rajesh, Zheng, Jie, Yan, Yangyang, Sigworth, Fred J.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2220058/
https://ncbi.nlm.nih.gov/pubmed/9041448
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