DNMT1 interacts with the developmental transcriptional repressor HESX1

Hesx1 is a highly conserved homeobox gene present in vertebrates, but absent from invertebrates. Gene targeting experiments in mice have shown that this transcriptional repressor is required for normal forebrain and pituitary development. In humans, mutations in HESX1 impairing either its repressing...

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Autores principales: Sajedi, Ezat, Gaston-Massuet, Carles, Andoniadou, Cynthia L., Signore, Massimo, Hurd, Paul J., Dattani, Mehul, Martinez-Barbera, Juan Pedro
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Pub. Co 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233781/
https://ncbi.nlm.nih.gov/pubmed/17931718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2007.08.010
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