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Permeation Properties of Inward-Rectifier Potassium Channels and Their Molecular Determinants

The structural domains contributing to ion permeation and selectivity in K channels were examined in inward-rectifier K(+) channels ROMK2 (Kir1.1b), IRK1 (Kir2.1), and their chimeras using heterologous expression in Xenopus oocytes. Patch-clamp recordings of single channels were obtained in the cell...

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Détails bibliographiques
Auteurs principaux: Choe, Han, Sackin, Henry, Palmer, Lawrence G.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233762/
https://ncbi.nlm.nih.gov/pubmed/10736307
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