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Different Fast-Gate Regulation by External Cl(−) and H(+) of the Muscle-Type Clc Chloride Channels

The fast gate of the muscle-type ClC channels (ClC-0 and ClC-1) opens in response to the change of membrane potential (V). This gating process is intimately associated with the binding of external Cl(−) to the channel pore in a way that the occupancy of Cl(−) on the binding site increases the channe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Mei-Fang, Chen, Tsung-Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233746/
https://ncbi.nlm.nih.gov/pubmed/11429442
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