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Cftr: Covalent Modification of Cysteine-Substituted Channels Expressed in Xenopus Oocytes Shows That Activation Is Due to the Opening of Channels Resident in the Plasma Membrane

Some studies of CFTR imply that channel activation can be explained by an increase in open probability (P(o)), whereas others suggest that activation involves an increase in the number of CFTR channels (N) in the plasma membrane. Using two-electrode voltage clamp, we tested for changes in N associat...

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Autori principali: Liu, Xuehong, Smith, Stephen S., Sun, Fang, Dawson, David C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233697/
https://ncbi.nlm.nih.gov/pubmed/11585853
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