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Mechanism of Irk1 Channel Block by Intracellular Polyamines
Intracellular polyamines inhibit the strongly rectifying IRK1 potassium channel by a mechanism different from that of a typical ionic pore blocker such as tetraethylammonium. As in other K(+) channels, in the presence of intracellular TEA, the IRK1 channel current decreases with increasing membrane...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2232894/ https://ncbi.nlm.nih.gov/pubmed/10828252 |
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