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Production of highly knotted DNA by means of cosmid circularization inside phage capsids

BACKGROUND: The formation of DNA knots is common during biological transactions. Yet, functional implications of knotted DNA are not fully understood. Moreover, potential applications of DNA molecules condensed by means of knotting remain to be explored. A convenient method to produce abundant highl...

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Main Authors: Trigueros, Sonia, Roca, Joaquim
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231350/
https://ncbi.nlm.nih.gov/pubmed/18154674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-7-94
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