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Knotting probability of DNA molecules confined in restricted volumes: DNA knotting in phage capsids

When linear double-stranded DNA is packed inside bacteriophage capsids, it becomes highly compacted. However, the phage is believed to be fully effective only if the DNA is not entangled. Nevertheless, when DNA is extracted from a tailless mutant of the P4 phage, DNA is found to be cyclic and knotte...

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Detalhes bibliográficos
Main Authors: Arsuaga, Javier, Vázquez, Mariel, Trigueros, Sonia, Sumners, De Witt, Roca, Joaquim
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122776/
https://ncbi.nlm.nih.gov/pubmed/11959991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032095099
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