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Antisense to MDR1 mRNA reduces P-glycoprotein expression, swelling-activated Cl(−) current and volume regulation in bovine ciliary epithelial cells
1. Native ciliary epithelial cells from the ciliary epithelium of the eye exhibit anti-P-glycoprotein (P-gp) immunofluorescence. 2. We have used an antisense ‘knock-down’ approach to investigate the relationship between P-gp and the volume-activated chloride current (I(Cl,swell)) and its role in vol...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2231096/ https://ncbi.nlm.nih.gov/pubmed/9679161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.033bi.x |
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