Inhibition of oxidative metabolism increases persistent sodium current in rat CA1 hippocampal neurons

1. Whole-cell patch-clamp recordings from freshly dissociated rat CA1 neurons revealed a large transient Na(+) current (I(Na,T)) and a smaller, inactivation-resistant persistent Na(+) current (I(Na,P)). Both currents could be blocked with TTX. 2. The average current densities of I(Na,T) and I(Na,P)...

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Detalhes bibliográficos
Main Authors: Hammarström, A K M, Gage, P W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231084/
https://ncbi.nlm.nih.gov/pubmed/9660889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.735bj.x
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