Cat cerebral arterial smooth muscle cells express cytochrome P450 4A2 enzyme and produce the vasoconstrictor 20-HETE which enhances L-type Ca(2+) current

1. Cerebral arteries express cytochrome P450 4A enzymes (P450 4A) and produce 20- hydroxyeicosatetraenoic acid (20-HETE), a potent constrictor of pial arterioles. It is not known which cell type in the vessel wall is responsible for the formation of 20-HETE. We examined whether freshly isolated cere...

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Autores principales: Gebremedhin, Debebe, Lange, Andrew R, Narayanan, Jayashree, Aebly, Mikael R, Jacobs, Elizabeth R, Harder, David R
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1998
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230829/
https://ncbi.nlm.nih.gov/pubmed/9508838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.771bs.x
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