Internal Mg(2+) block of recombinant NMDA channels mutated within the selectivity filter and expressed in Xenopus oocytes

1. The NMDA receptor channel is blocked by both external and internal Mg(2+) ions, which are assumed to bind inside the channel on each side of a central barrier. We have analysed the internal Mg(2+) block in recombinant NR1-NR2A NMDA receptors expressed in Xenopus oocytes. We have determined the ef...

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Autores principales: Kupper, Jürgen, Ascher, Philippe, Neyton, Jacques
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1998
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230784/
https://ncbi.nlm.nih.gov/pubmed/9490808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.001bu.x
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