Properties of human glycine receptors containing the hyperekplexia mutation α1(K276E), expressed in Xenopus oocytes

1. Inherited defects in human glycine receptors give rise to hyperekplexia (startle disease). We expressed human glycine receptors in Xenopus oocytes, in order to examine the pharmacological and single-channel properties of receptors that contain a mutation, α1(K276E), associated with an atypical fo...

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Detalhes bibliográficos
Main Authors: Lewis, T M, Sivilotti, L G, Colquhoun, D, Gardiner, R M, Schoepfer, R, Rees, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230779/
https://ncbi.nlm.nih.gov/pubmed/9490812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.025bu.x
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