The NECAP PHear domain increases clathrin accessory protein binding potential

AP-2 is a key regulator of the endocytic protein machinery driving clathrin-coated vesicle (CCV) formation. One critical function, mediated primarily by the AP-2 α-ear, is the recruitment of accessory proteins. NECAPs are α-ear-binding proteins that enrich on CCVs. Here, we have solved the structure...

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Bibliographische Detailangaben
Hauptverfasser: Ritter, Brigitte, Denisov, Alexei Yu, Philie, Jacynthe, Allaire, Patrick D, Legendre-Guillemin, Valerie, Zylbergold, Peter, Gehring, Kalle, McPherson, Peter S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230672/
https://ncbi.nlm.nih.gov/pubmed/17762867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601836
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