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The NECAP PHear domain increases clathrin accessory protein binding potential
AP-2 is a key regulator of the endocytic protein machinery driving clathrin-coated vesicle (CCV) formation. One critical function, mediated primarily by the AP-2 α-ear, is the recruitment of accessory proteins. NECAPs are α-ear-binding proteins that enrich on CCVs. Here, we have solved the structure...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2230672/ https://ncbi.nlm.nih.gov/pubmed/17762867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601836 |
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