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PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans

Autophagy is a process by which cells recycle cytoplasm and defective organelles during stress situations such as nutrient starvation. It can also be used by host cells as an immune defense mechanism to eliminate infectious pathogens. Here we describe the use of autophagy as a survival mechanism and...

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Dettagli Bibliografici
Autori principali: Hu, Guowu, Hacham, Moshe, Waterman, Scott R., Panepinto, John, Shin, Soowan, Liu, Xiaoguang, Gibbons, Jack, Valyi-Nagy, Tibor, Obara, Keisuke, Jaffe, H. Ari, Ohsumi, Yoshinori, Williamson, Peter R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230655/
https://ncbi.nlm.nih.gov/pubmed/18259613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32053
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