PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans

Autophagy is a process by which cells recycle cytoplasm and defective organelles during stress situations such as nutrient starvation. It can also be used by host cells as an immune defense mechanism to eliminate infectious pathogens. Here we describe the use of autophagy as a survival mechanism and...

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Autores principales: Hu, Guowu, Hacham, Moshe, Waterman, Scott R., Panepinto, John, Shin, Soowan, Liu, Xiaoguang, Gibbons, Jack, Valyi-Nagy, Tibor, Obara, Keisuke, Jaffe, H. Ari, Ohsumi, Yoshinori, Williamson, Peter R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230655/
https://ncbi.nlm.nih.gov/pubmed/18259613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32053
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