PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans

Autophagy is a process by which cells recycle cytoplasm and defective organelles during stress situations such as nutrient starvation. It can also be used by host cells as an immune defense mechanism to eliminate infectious pathogens. Here we describe the use of autophagy as a survival mechanism and...

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Bibliografiske detaljer
Main Authors: Hu, Guowu, Hacham, Moshe, Waterman, Scott R., Panepinto, John, Shin, Soowan, Liu, Xiaoguang, Gibbons, Jack, Valyi-Nagy, Tibor, Obara, Keisuke, Jaffe, H. Ari, Ohsumi, Yoshinori, Williamson, Peter R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230655/
https://ncbi.nlm.nih.gov/pubmed/18259613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32053
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