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A Mutation Linked with Bartter's Syndrome Locks Kir 1.1a (Romk1) Channels in a Closed State

Mutations in the inward rectifying renal K(+) channel, Kir 1.1a (ROMK), have been linked with Bartter's syndrome, a familial salt-wasting nephropathy. One disease-causing mutation removes the last 60 amino acids (332–391), implicating a previously unappreciated domain, the extreme COOH terminus...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Flagg, Thomas P., Tate, Margaret, Merot, Jean, Welling, Paul A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230538/
https://ncbi.nlm.nih.gov/pubmed/10532965
Tagiau: Ychwanegu Tag
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