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NO-Evoked macrophage apoptosis is attenuated by cAMP-induced gene expression.

BACKGROUND: Previous work has suggested that an increase in expression of cyclooxygenase-2, concomitant formation of E-type prostanoids, and in turn intracellular cAMP conveys macrophage resistance against apoptosis. MATERIALS AND METHODS: We analyzed the effects of lipophilic cAMP analogs on nitric...

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Bibliographic Details
Main Authors: von Knethen, A., Brockhaus, F., Kleiter, I., Brüne, B.
Format: Artigo
Language:Inglês
Published: The Feinstein Institute for Medical Research 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230476/
https://ncbi.nlm.nih.gov/pubmed/10602776
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