Peptidomimetic fluoromethylketone rescues mice from lethal endotoxic shock.

BACKGROUND: Septic shock is a leading cause of mortality in intensive care units. No new interventions in the last 20 years have made a substantial impact on the outcome of patients with septic shock. Identification of inhibitable pathways that mediate death in shock is an important goal. MATERIALS...

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Main Authors: Grobmyer, S. R., Armstrong, R. C., Nicholson, S. C., Gabay, C., Arend, W. P., Potter, S. H., Melchior, M., Fritz, L. C., Nathan, C. F.
Format: Artigo
Sprog:Inglês
Udgivet: The Feinstein Institute for Medical Research 1999
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230465/
https://ncbi.nlm.nih.gov/pubmed/10551900
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