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Peptidomimetic fluoromethylketone rescues mice from lethal endotoxic shock.

BACKGROUND: Septic shock is a leading cause of mortality in intensive care units. No new interventions in the last 20 years have made a substantial impact on the outcome of patients with septic shock. Identification of inhibitable pathways that mediate death in shock is an important goal. MATERIALS...

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Hlavní autoři: Grobmyer, S. R., Armstrong, R. C., Nicholson, S. C., Gabay, C., Arend, W. P., Potter, S. H., Melchior, M., Fritz, L. C., Nathan, C. F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Feinstein Institute for Medical Research 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230465/
https://ncbi.nlm.nih.gov/pubmed/10551900
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