Protection against hyperacute xenograft rejection of transgenic rat hearts expressing human decay accelerating factor (DAF) transplanted into primates.

BACKGROUND: Production of transgenic pigs for multiple transgenes is part of a potential strategy to prevent immunological events involved in xenograft rejection. Use of a genetically engineerable rodent as a donor in primates could allow testing in vivo of the effects of different transgenes on con...

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Main Authors:	Charreau, B., MÃ©noret, S., Tesson, L., Azimzadeh, A., Audet, M., Wolf, P., Marquet, R., Verbakel, C., Ijzermans, J., Cowan, P., Pearse, M., d'Apice, A., Soulillou, J. P., Anegon, I.
Format:	Artigo
Sprog:	Inglês
Udgivet:	The Feinstein Institute for Medical Research 1999
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2230462/ https://ncbi.nlm.nih.gov/pubmed/10551903
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Protection against hyperacute xenograft rejection of transgenic rat hearts expressing human decay accelerating factor (DAF) transplanted into primates.

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