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The 12 kD FK 506 binding protein FKBP12 is released in the male reproductive tract and stimulates sperm motility.

BACKGROUND: The 12 kD FK506 binding protein FKBP12 is a cytosolic receptor for the immunosuppressant drugs FK506 and rapamycin. In addition to its critical role in drug-induced T-cell immunosuppression, FKBP12 associates physiologically with ryanodine and inositol 1,4,5-trisphosphate (IP3) receptors...

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Detalhes bibliográficos
Main Authors: Walensky, L. D., Dawson, T. M., Steiner, J. P., Sabatini, D. M., Suarez, J. D., Klinefelter, G. R., Snyder, S. H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute for Medical Research 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230403/
https://ncbi.nlm.nih.gov/pubmed/9742506
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