Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production.

BACKGROUND: The hydrophilic bile salt ursodeoxycholate (UDCA) inhibits injury by hydrophobic bile acids and is used to treat cholestatic liver diseases. Interestingly, hepatocyte cell death from bile acid-induced toxicity occurs more frequently from apoptosis than from necrosis. However, both proces...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rodrigues, C. M., Fan, G., Wong, P. Y., Kren, B. T., Steer, C. J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Feinstein Institute for Medical Research 1998
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230355/
https://ncbi.nlm.nih.gov/pubmed/9562975
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