The beta c component of the granulocyte-macrophage colony-stimulating factor (GM-CSF)/interleukin 3 (IL-3)/IL-5 receptor interacts with a hybrid GM-CSF/erythropoietin receptor to influence proliferation and beta-globin mRNA expression.

BACKGROUND: The interaction of different members of the hematopoietic growth factor receptor family may be relevant to the increased proliferation and the failure of differentiation that characterizes the myeloid leukemias. We recently demonstrated that a chimeric receptor (GMER) that is composed of...

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Hauptverfasser: Jubinsky, P. T., Shikama, Y., Laurie, A., Nathan, D. G., Carroll, M., Sieff, C. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Feinstein Institute for Medical Research 1996
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230139/
https://ncbi.nlm.nih.gov/pubmed/8972491
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