Parathyroid hormone-related protein is induced during lethal endotoxemia and contributes to endotoxin-induced mortality in rodents.

BACKGROUND: Parathyroid hormone-related protein (PTHrP) is a ubiquitous and highly conserved vasoactive peptide whose role and regulation in normal physiology remain an enigma. Recently, we demonstrated that low-dose endotoxin (LPS) induces intrasplenic, but not systemic, levels of PTHrP; and that t...

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Main Authors: Funk, J. L., Moser, A. H., Strewler, G. J., Feingold, K. R., Grünfeld, C.
Format: Artigo
Sprog:Inglês
Udgivet: The Feinstein Institute for Medical Research 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230122/
https://ncbi.nlm.nih.gov/pubmed/8726463
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