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Knockout of the mu opioid receptor enhances the survival of adult-generated hippocampal granule cell neurons

Recent evidence suggests that mu opioid receptors (MOR) are key regulators of hippocampal structure and function. For example, exogenous MOR agonists morphine and heroin negatively impact hippocampal function and decrease adult hippocampal neurogenesis. Here we explored the role of MOR in the birth...

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Detalhes bibliográficos
Main Authors: Harburg, Gwyndolen C., Hall, F. Scott, Harrist, Alexia V., Sora, Ichiro, Uhl, George R., Eisch, Amelia J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230097/
https://ncbi.nlm.nih.gov/pubmed/17055658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2006.09.018
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