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The 55-kD tumor necrosis factor receptor and CD95 independently signal murine hepatocyte apoptosis and subsequent liver failure.

BACKGROUND: Activation of either the 55-kD tumor necrosis factor receptor (TNF-R1) or CD95 (Fas/Apo-1) causes apoptosis of cells and liver failure in mice, and has been associated with human liver disorders. The aim of this study was first to clarify the association between CD95 activation, hepatocy...

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Bibliografiske detaljer
Main Authors: Leist, M., Gantner, F., Künstle, G., Bohlinger, I., Tiegs, G., Bluethmann, H., Wendel, A.
Format: Artigo
Sprog:Inglês
Udgivet: The Feinstein Institute for Medical Research 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230024/
https://ncbi.nlm.nih.gov/pubmed/8900539
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