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Role of macrophage oxidative burst in the action of anthrax lethal toxin.

BACKGROUND: Major symptoms and death from systemic Bacillus anthracis infections are mediated by the action of the pathogen's lethal toxin on host macrophages. High levels of the toxin are cytolytic to macrophages, whereas low levels stimulate these cells to produce cytokines (interleukin-1 bet...

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Autori principali: Hanna, P. C., Kruskal, B. A., Ezekowitz, R. A., Bloom, B. R., Collier, R. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Feinstein Institute for Medical Research 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229935/
https://ncbi.nlm.nih.gov/pubmed/8790597
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