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Pentoxifylline and other protein kinase C inhibitors down-regulate HIV-LTR NF-kappa B induced gene expression.

BACKGROUND: This investigation deals with the molecular mechanism of anti-human immunodeficiency virus type 1 (HIV-1) action of pentoxifylline (PTX) [1-(5'-oxohexyl)-3, 7-dimethylxanthine] a drug widely used for the treatment of conditions involving defective regional microcirculation. MATERIAL...

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Main Authors: Biswas, D. K., Ahlers, C. M., Dezube, B. J., Pardee, A. B.
Format: Artigo
Jezik:Inglês
Izdano: The Feinstein Institute for Medical Research 1994
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229934/
https://ncbi.nlm.nih.gov/pubmed/8790599
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