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A Marine Snail Neurotoxin Shares with Scorpion Toxins a Convergent Mechanism of Blockade on the Pore of Voltage-Gated K Channels

κ-Conotoxin-PVIIA (κ-PVIIA) belongs to a family of peptides derived from a hunting marine snail that targets to a wide variety of ion channels and receptors. κ-PVIIA is a small, structurally constrained, 27-residue peptide that inhibits voltage-gated K channels. Three disulfide bonds shape a charact...

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Autors principals: García, Esperanza, Scanlon, Martin, Naranjo, David
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229644/
https://ncbi.nlm.nih.gov/pubmed/10398697
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