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Tracking Voltage-dependent Conformational Changes in Skeletal Muscle Sodium Channel during Activation

The primary voltage sensor of the sodium channel is comprised of four positively charged S4 segments that mainly differ in the number of charged residues and are expected to contribute differentially to the gating process. To understand their kinetic and steady-state behavior, the fluorescence signa...

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Detalles Bibliográficos
Main Authors: Chanda, Baron, Bezanilla, Francisco
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2002
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229551/
https://ncbi.nlm.nih.gov/pubmed/12407076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028679
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