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Gating and Conductance Properties of Bk Channels Are Modulated by the S9–S10 Tail Domain of the α Subunit: A Study of Mslo1 and Mslo3 Wild-Type and Chimeric Channels

The COOH-terminal S9–S10 tail domain of large conductance Ca(2+)-activated K(+) (BK) channels is a major determinant of Ca(2+) sensitivity (Schreiber, M., A. Wei, A. Yuan, J. Gaut, M. Saito, and L. Salkoff. 1999. Nat. Neurosci. 2:416–421). To investigate whether the tail domain also modulates Ca(2+)...

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Detalles Bibliográficos
Main Authors: Moss, Brenda L., Magleby, Karl L.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2001
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229511/
https://ncbi.nlm.nih.gov/pubmed/11723163
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