Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion
Activator protein-1 (AP-1) is a transcription factor that consists of either a Jun-Jun homodimer or a Jun-Fos heterodimer. Transactivation of AP-1 is required for tumor promoter-induced transformation in mouse epidermal JB6 cells and for progression in mouse and human keratinocytes. Until now, the q...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22295/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449779/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9827 |
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