Mg(2+) Modulates Voltage-Dependent Activation in Ether-à-Go-Go Potassium Channels by Binding between Transmembrane Segments S2 and S3

Extracellular Mg(2+) directly modulates voltage-dependent activation in ether-à-go-go (eag) potassium channels, slowing the kinetics of ionic and gating currents (Tang, C.-Y., F. Bezanilla, and D.M. Papazian. 2000. J. Gen. Physiol. 115:319-337). To exert its effect, Mg(2+) presumably binds to a site...

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Main Authors: Silverman, William R., Tang, Chih-Yung, Mock, Allan F., Huh, Kyung-Bong, Papazian, Diane M.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2000
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229486/
https://ncbi.nlm.nih.gov/pubmed/11055995
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