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P-loop Flexibility in Na(+) Channel Pores Revealed by Single- and Double-cysteine Replacements
Replacement of individual P-loop residues with cysteines in rat skeletal muscle Na(+) channels (SkM1) caused an increased sensitivity to current blockade by Cd(2+) thus allowing detection of residues lining the pore. Simultaneous replacement of two residues in distinct P-loops created channels with...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
1997
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229360/ https://ncbi.nlm.nih.gov/pubmed/9234171 |
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