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Topology of the P segments in the sodium channel pore revealed by cysteine mutagenesis.

The P segments of the voltage-dependent Na+ channel line the outer mouth and selectivity filter of the pore. The residues that form the cytoplasmic mouth of the pore of the channel have not been identified. To study the structure of the inner pore mouth, the presumed selectivity filter residues (D40...

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Autors principals: Yamagishi, T, Janecki, M, Marban, E, Tomaselli, G F
Format: Artigo
Idioma:Inglês
Publicat: 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180921/
https://ncbi.nlm.nih.gov/pubmed/9199784
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