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Binding affinity and stereoselectivity of local anesthetics in single batrachotoxin-activated Na+ channels

Several local anesthetics (LA) have been previously shown to block muscle batrachotoxin (BTX)-activated Na+ channels in planar bilayers. The mean dwell time of different LA drugs, however, varies widely, from less than 10 ms to longer than several seconds. In this study, we have examined the structu...

詳細記述

保存先:
書誌詳細
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229022/
https://ncbi.nlm.nih.gov/pubmed/2177771
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