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A central role for thymic emigrants in peripheral T cell homeostasis

After initial seeding by thymic emigrants, homeostatic regulation of the T cell pool has been thought to occur entirely within the periphery. Here we report that the degree of thymic emigration directly affects the number and the CD4/CD8 ratio of peripheral T cells. We demonstrate that the increase...

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Autori principali: Berzins, S. P., Godfrey, D. I., Miller, J. F. A. P., Boyd, R. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC22288/
https://ncbi.nlm.nih.gov/pubmed/10449772
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