A central role for thymic emigrants in peripheral T cell homeostasis
After initial seeding by thymic emigrants, homeostatic regulation of the T cell pool has been thought to occur entirely within the periphery. Here we report that the degree of thymic emigration directly affects the number and the CD4/CD8 ratio of peripheral T cells. We demonstrate that the increase...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22288/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10449772/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.17.9787 |
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