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An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro

Multimeric peptide/class II MHC staining reagents were synthesized and shown to bind with appropriate specificity to T cell hybridomas. A small, expanded population of T cells detected with one of these reagents in peptide-immunized C57BL/10 mice persisted for several months. This population expande...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rees, William, Bender, Jeremy, Teague, T. Kent, Kedl, Ross M., Crawford, Frances, Marrack, Philippa, Kappler, John
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC22287/
https://ncbi.nlm.nih.gov/pubmed/10449771
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