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Modified kinetics and selectivity of sodium channels in frog skeletal muscle fibers treated with aconitine

The effect of the plant alkaloid aconitine on sodium channel kinetics, ionic selectivity, and blockage by protons and tetrodotoxin (TTX) has been studied in frog skeletal muscle. Treatment with 0.25 or 0.3 mM aconitine alters sodium channels so that the threshold of activation is shifted 40-50 mV in...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1982
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228644/
https://ncbi.nlm.nih.gov/pubmed/6294221
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