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Interactions of neosaxitoxin with the sodium channel of the frog skeletal muscle fiber

Neosaxitoxin (neoSTX) differs structurally from saxitoxin (STX) in that the hydrogen on N-1 is replaced by a hydroxyl group. On single frog skeletal muscle fibers in the vaseline-gap voltage clamp, the concentrations for reducing the maximum sodium current by 50% (ED50) at pH's 6.50, 7.25, and...

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Detalhes bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216488/
https://ncbi.nlm.nih.gov/pubmed/1645395
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