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Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for glial and neural-related molecules in central nervous system mixed glial cell cultures: neurotrophins, growth factors and structural proteins

BACKGROUND: In multiple sclerosis, inflammatory cells are found in both active and chronic lesions, and it is increasingly clear that cytokines are involved directly and indirectly in both formation and inhibition of lesions. We propose that cytokine mixtures typical of Th1 or Th2 lymphocytes, or mo...

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Autors principals: Lisak, Robert P, Benjamins, Joyce A, Bealmear, Beverly, Nedelkoska, Liljana, Yao, Bin, Land, Susan, Studzinski, Diane
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228280/
https://ncbi.nlm.nih.gov/pubmed/18088439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-4-30
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